Searchable abstracts of presentations at key conferences in endocrinology

ea0012p49 | Diabetes, metabolism and cardiovascular | SFE2006

Relation of free and bound leptin and the soluble leptin receptor to metabolic and inflammatory responses in patients with liver cirrhosis

Ockenga J , Tietge UJF , Bahr MJ , Brabant G

Leptin circulates as a free (FL) and a protein-bound (BL) form, with the soluble leptin receptor (LR) as an important binding compound. This study was set out to address the distinct role of the leptin components in the metabolic and inflammatory tissue-repair response in patients with liver cirrhosis.MethodsWe investigated hepatic substrate and leptin metabolism in 40 cirrhotics employing a combination of arterial and hepatic vein...